Case Study: PRS High-Risk Patient Uses HOME2 to Avoid Vision Loss

Names and details changed for privacy.

‘Evelyn,’ a 52-year-old with a family history of glaucoma, ordered the MyEyes PRS Genetic Test after her sister lost peripheral vision. Her polygenic risk score came back in the 93rd percentile — high enough that her doctor wanted closer monitoring even though her optic nerves still looked healthy.

Week 1: Baseline Data

Evelyn rented an iCare HOME2 and measured four times daily (morning, noon, evening, bedtime). Median IOP: 17 mmHg, but she noticed occasional 23 mmHg spikes at 10 p.m.

Week 2: Nighttime Focus

Following coaching from a MyEyes Patient Ambassador, she added 2 a.m. readings. Boom: pressures hit 27–28 mmHg while lying down. Those spikes never showed up during daytime clinic visits.

Week 3: Doctor Review

Her ophthalmologist reviewed the annotated report and immediately tightened her target pressure to 14 mmHg. They switched her to a preservative-free prostaglandin and scheduled SLT within the month.

Week 6: Post-SLT Monitoring

HOME2 readings dropped to a median of 13 mmHg with no spikes above 18 mmHg. The doctor cancelled a planned MIGS consult because the combination of SLT plus lifestyle changes (elevating her pillow, treating mild sleep apnea) stabilized her curve.

Key Lessons

• Genetics informed urgency: A high PRS score justified immediate action.
• Home monitoring guided therapy: The doctor could see exactly when pressures exceeded safe levels.
• Early intervention preserved nerve tissue: OCT scans six months later showed no structural loss.

If Evelyn had waited for visual field changes, she may have lost function permanently. Genetic risk plus daily HOME2 measurements gave her team a six-month head start.

Want a similar safety net? Combine the PRS test with a HOME2 rental or purchase and let our ambassadors show you how to build actionable reports.